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However, there is only one approved drug, setmelanotide for POMC-LEPR deficiency [10], and there is no treatment for other POMC-MC4R pathway-deficient diseases, such as POMC-null, MSH-deficiency, and patients with PWS with obesity

doi: 10.1038/s41569-023-00849-3, PMID: [DOI] [PubMed] [Google Scholar] 9

Tirzepatide can affect hormonal balance in ways that indirectly influence bladder function

8 Broad Benefits: In a broader population with or without diabetes, GLP-1 RA use was associated with a 17% lower cancer incidence

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These drugs are part of an emerging class of nutrient-stimulated hormone-based therapeutics, acting as incretin mimetics to target G-proteincoupled receptors like GLP-1, glucose-dependent insulinotropic polypeptide (GIP), and glucagon