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Its used for type 2 diabetes and has a recently approved cardiovascular label extension, and one oral semaglutide product in development for obesity and cardiovascular risk reduction

10.1111/jdi.13544 [DOI] [PMC free article] [PubMed] [Google Scholar] 89.Dhanapalaratnam R, Issar T, Lee ATK, Poynten AM, Milner KL, Kwai NCG, Krishnan AV (2024) Glucagon-like peptide-1 receptor agonists reverse nerve morphological abnormalities in diabetic peripheral neuropathy

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For a weekly injection schedule where vials remain in use for 4-10 weeks, stability matters significantly

In the POUNDS Lost trial, adults with overweight or obesity following calorie-restricted diets lost more weight and were more likely to stay on their plan when they ate more dietary fiber , independent of the overall macronutrient split