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Rising blood glucose levels signal the pancreas to release insulin from specialized -cells

CARDIOVASCULAR EFFECTS OF GLP-1 RAs IN HUMAN STUDIES Blood pressure and heart rate Circulating biomarkers and lipid profiles Carotid intima-media thickness LV function and reperfusion injury in patients with coronary artery disease Retrospective studies on cardiovascular outcomes A prospective randomized clinical trial with primary cardiovascular outcome: the ELIXA study Preclinical and preliminary clinical evidence has consistently revealed potential cardiovascular benefits from the administration of GLP-1 RAs

Appetite regulation : Acts on the hypothalamus to promote satiety and reduce food intake

If the 2.4 mg dose is not tolerated, 1.7 mg weekly is an FDA-approved maintenance alternative

[4,5] Safety: symptoms that should not be treated as a plateau Some symptoms need medical advice immediately

[1] Dehydration from gastrointestinal side effects can increase the risk of acute kidney injury