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The outcomes from Part 1 of the ESSENCE Phase 3 clinical trial were recently reported in detail by Sanyal et al

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CrossRef Glucose tasting depletes intracellular calcium stores and impairs macrophage functionality Laura Schlautmann, Daniel Burgdorf, Shaunak Ghosh, Alina Schieren, Linda Klmpen, Isabel Sttzel, Julia Bremser, Michael Dngi, Elvira Mass, Valentin Stein, Thomas Quast, Waldemar Kolanus, Thorsten Lang, Eva Kiermaier, Marie-Christine Simon, Sven Burgdorf iScience.2025

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No published clinical human trial demonstrating measurable GLP-1 level changes from this specific product is known to this publication
