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While the issues with model validity, model transparency, and the predictive parameters of the model resulted in high uncertainty in the models results, CADTH undertook an exploratory analysis to assess the impact of a small change in the impact of treatment administration on the cost-effectiveness of semaglutide

Emerging evidence suggests that dual GIP/GLP-1 receptor agonists and triple GIP/GLP-1/glucagon receptor agonists provide beneficial metabolic effects in individuals with type 2 diabetes and obesity

doi: 10.1002/jnr.21349 137 AdriaenssensAEBiggsEKDarwishTTadrossJSukthankarTGirishMet al

"Novo Nordisk is of the opinion that the benefit-risk profile of semaglutide remains unchanged, she told Newsday