glp 1 shot alternative GLP-1 Compounds: A Cheaper or a Risky Gamble? Weight loss pills may soon
Description
Glycaemic control typically improves within the first few weeks, whilst significant weight loss and associated energy improvements may take 3-6 months to become apparent
June 7-11, 2019
PMID 40471562
When given to obese mice, LY3437943 decreased body weight and enhanced glycemic/blood sugar control
They postulate that the enhanced export of bile acids out of hepatocytes and a reduction of bile acid synthesis via inhibition of CYP7A1, which converts cholesterol to bile acids, were mediated by increased GLP-1 in DPP4-KO rats (48)
Current and prospective manufacturers of biosimilars covered under the pharmacy benefit face the perennial questions about this market
