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While these are not directly linked to kidney damage, dehydration (from nausea, vomiting or diarrhea) can worsen kidney function in some individuals

Gastroparesis is a medical condition in which the patients stomach does not empty properly

Consumer fraud is another risk, as such companies may take your money, but not deliver the medication

however, concomitant metformin therapy was not associated with an increased risk of GI symptoms, or an increased likelihood of GLP-1 RA discontinuation, compared to those who were not taking metformin

Morgan Global Research, 29 Nov

They do lead to weight loss on their own, but results are much better when paired with healthy eating and physical activity