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The combination is generally well-tolerated, but potential side effects include fatigue, headache, or dizziness from Zofran, alongside semaglutide-related effects like nausea, diarrhea, or reduced appetite

If we can get through March Madness without a hospitalization, then we will know this is a real thing, Palmer explained

Semaglutide works by slowing food movement within the intestines so that you feel fuller for longer by mimicking the hormones the body creates when digesting food within the intestinal system
As muscles adapt to reduced glycogen stores, localized spasms may occur, particularly in larger muscle groups

Handbook of experimental pharmacology , Vol 123
