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If you have injection site pain with Emgality, you can help reduce it by: applying a warm or cool compress to the injection site taking an over-the-counter (OTC) pain medication such as acetaminophen (Tylenol) or ibuprofen (Advil, Motrin) Most Emgality injection site reactions go away Talk with your doctor if you have severe, ongoing, or worsening pain after your Emgality injections

Generally, you shouldnt experience fatigue, low energy, hypoglycemia, or long-term nausea while taking GLP-1s, Obici says

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This article provides evidence-based guidance on safely administering GLP-1 injections in the thigh

Mottalib A, Abrahamson MJ, Pober DM, Polak R, Eldib AH, Tomah S, Ashrafzadeh S, Hamdy O