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doi: 10.1016/S0140-6736(19)31149-3 [DOI] [PubMed] [Google Scholar] 43

This is important because GLP-1 drugs were originally designed to have a long half-life in blood to maximise their efficacy in the treatment of diabetes which prevents them from entering the brain (Hlscher)

If you are new to GLP-1 medications, invest time in educating yourself before starting

(16) uncover a potential dark side of excessive central GLP-1 signaling

Nobody wants to deal with urgent GI symptoms during a morning commute

In patients continuing GLP-1RA therapy, the use of point-of-care gastric ultra sound may be a reasonable strategy to enhance patient safety and prevent unnecessary surgical cancellations