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Eating an amino acid rich meal, being in a state of hypoglycemia, or stimulation from the autonomic nervous system can stimulate the pancreas to release glucagon which binds to G protein coupled receptors on skeletal muscle and the liver

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Cardiovascular events and all-cause mortality with insulin versus glucagon-like peptide-1 analogue in type 2 diabetes

doi: 10.1016/j.rbmo.2022.01.007 122 ZhangFLiSPZhangTYuBZhangJDingHGet al