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A 2026 review in Drugs lays out the clinical tension clearly: maternal obesity + excess gestational weight gain drive major short- and long-term risks for both mother and baby, while lifestyle-only strategies often deliver modest resultscreating a real unmet need

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Nevertheless, the certainty of the effect size following the GRADE classification was very low. Conclusions In this systematic review and meta-analysis, we found that GLP-1 RAs significantly prolonged gastric emptying T by a mean of 74min, which could have implications for perioperative care

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