mapping the effectiveness and risks of glp-1 receptor agonists pdf agonism: a transformative approach for managing type-2 diabetes obesity Mapping the effectiveness and risks

Obesity and insulin resistance sustain elevated circulating concentrations of pro-inflammatory cytokines including Tumour Necrosis Factor-alpha (TNF-), Interleukin-1 (IL-1), and Interleukin-6 (IL-6) molecules that promote DNA damage, tumour angiogenesis, and immune evasion

[DOI] [PubMed] [Google Scholar] 58.Feng J., Zhang Z., Wallace M.B., Stafford J.A., Kaldor S.W., Kassel D.B., Navre M., Shi L., Skene R.J., Asakawa T., et al

GLP-1 also affects food intake, body weight, and has direct effects on the heart (52, 103)

10.1007/s00125-014-3231-y [DOI] [PubMed] [Google Scholar] 47.Pinto LC, Rados DV, Barkan SS, Leitao CB, Gross JL

These agents are likely to vary widely in their affinity and potency at each hormone receptor

Mind you, I am not being optimistic here, this is not a everyone will make better choices in their diet assessment