retatrutide dos A Clinician's Guide to Dosing Retatrutide vs. semaglutide: A head-to-head

Description

doi: 10.2147/TCRM 117 GrugniGGiardinoDCrinAMalvestitiFBallaratiLDi GiorgioGet al

M., Jones, K

Regulatory status is relevant for those anticipating retatrutides application to fight hard-to-lose fat

This research highlights that there are several studies under development that may bring additional results in the continuation or replication of the use of SMG in patients with obesity and/or DM2 but also investigate new combinations (e.g., combination with dehydrated cannabidiolNCT06648031) compared to new drugs (NCT06649344, NCT06604624, NCT06579105, NCT06577090, NCT06497049, NCT06282458, and NCT05616013) and may even expand the indications for other pathological conditions (associated or not with obesity or DM2), such as steroid-induced diabetes (NCT06318442), acute myocardial infarction (NCT06557811), autosomal dominant polycystic kidney disease (NCT06582875), steatohepatitis associated with metabolic dysfunction (NCT06492330 and NCT06374875), obesity-related asthma (NCT05254314), cystic fibrosis (NCT05788965), advanced interstitial lung disease (NCT05746039), psoriasis vulgaris (NCT06475586), systemic scleroderma (NCT06149260), idiopathic intracranial hypertension (NCT06361823 and NCT06027567), post-acute stroke (NCT05630586 and NCT05920889), neuroleptic-related prediabetes in individuals with schizophrenia (NCT05193578), Alzheimers (NCT06072963 and NCT05891496), functional hypogonadism (NCT06489457), polycystic ovary syndrome (NCT05646199, NCT05702905, NCT06222437, and NCT05819853), endometrial hyperplasia (NCT05829460), Klinefelters syndrome (NCT05586802), or even in alcohol consumption disorder (NCT05520775, NCT05891587, NCT05895643, and NCT05892432), opioid use (NCT06548490), or cocaine use with and without human immunodeficiency virus (NCT06691243), among many other potential therapeutic indications

Therefore, bariatric surgery in patients with PWS remains still controversial and requires the collaboration of an expert multidisciplinary team and the development of more innovative bariatric treatment plans tailored to patients with PWS to obtain effective and stable weight loss, and to reduce severe health complications in these patients Table 1