glp 1 agonist vs sglt2 inhibitor Recommendations for SGLT2i versus GLP-1 RA on the basis of kidney View of Diabetes medications with
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Some GLP-1 and related medications are approved for chronic weight management in eligible adults without diabetes

A total of 112 articles were initially identified through comprehensive database searches

25 Given concerns that skeletal muscle loss may predispose patients to long-term metabolic complications, including sarcopenia, it is recommended that individuals undergoing treatment with GLP-1 RAs receive adequate protein intake and appropriate micronutrient supplementation to preserve muscle mass and function, thereby maximizing the clinical benefits of therapy

Researchers are also evaluating retatrutide for type 2 diabetes (TRIUMPH-2), cardiovascular outcomes (TRIUMPH-3), and other conditions such as metabolic dysfunction-associated steatotic liver disease (MASLD)

ASAT, abdominal subcutaneous adipose tissue
