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19 Comparison with SGLT-2 inhibitors Both GLP-1RAs and SGLT-2 inhibitors reduce all-cause and cardiovascular mortality

Abstract Purpose of Review There has been a rise in popularity and use of GLP-1 receptor agonists since their approval for obesity management

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They work by: Enhancing insulin secretion in response to meals Reducing glucagon secretion (which helps lower blood sugar levels) Slowing gastric emptying, leading to increased satiety The efficacy of GLP-1 medications has led to their FDA approval for weight management, making them an attractive option for many individuals seeking to lose weight

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