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T cells, macrophages, adipocytes, and myocytes are among the cells secreting IL-6

GLP-1 itself is a gut-derived incretin hormone released by the enteroendocrine cells in response to nutrient intake

We investigated GLP1 receptor agonists at drug class level and liraglutide and semaglutide were the most commonly used individual drugs in the study

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in: PubMed | Google Scholar | 1 Ted Rogers Centre for Heart Research, University of Toronto, Toronto, Ontario, Canada

Polyphenols and certain spice compounds work through yet other pathways including inhibiting DPP-IV, the enzyme that breaks GLP-1 down within minutes of its release