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7 The following sections will discuss the overall approach to intensification of glucose-lowering agents, as illustrated in Figure 2 , with an emphasis on the role of GLP-1 RAs within the current recommendations

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These results suggest that the gut microbiota, the gut microbiota-derived NMN, and the intestinal NAMPTNAD + SIRT axis collaborate to regulate intestinal homeostasis and systemic metabolic functions (Figure

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