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Some patients find that keeping a simple injection log helps them track which sites they used and when, making rotation automatic rather than random
Patients with a history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2) should avoid these medications due to the potential risk of thyroid C-cell tumors

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In contrast the decrease of plasma aldosterone was observed by Baretic et al

After 4 weeks of 0.25 mg, increase dose to 0.5 mg once weekly
