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Seek urgent medical attention if light-headedness is accompanied by: Severe or persistent hypoglycaemia symptoms including confusion, sweating, tremor, palpitations, or difficulty concentrating Chest pain or palpitations which may indicate cardiovascular complications Severe dehydration signs include reduced urine output, dark urine, extreme thirst, or dry mucous membranes Fainting or loss of consciousness even brief episodes warrant investigation Visual disturbances blurred vision, double vision, or visual field defects Severe headache particularly if sudden onset or unlike previous headaches Difficulty breathing or speaking which may suggest a serious adverse reaction Call 999 immediately for severe chest pain, severe breathlessness, loss of consciousness, or symptoms of stroke

Furthermore, research published in the journal Obesity Science & Practice highlighted the benefits of semaglutide for long-term weight maintenance, demonstrating sustained reductions in body weight and improvements in obesity-related comorbidities over time

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On the other hand, Semaglutide primarily targets GLP-1 receptors

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Reduced glucose levels can also increase the production of ROS causing oxidation damage and interfere with signaling pathways and finally lead to apoptosis and necrosis [16] (Fig