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Before Zepbound, she estimates she spent two to three hours a day thinking about food (e.g., what to order, whether she'd been disciplined enough to justify what she was craving)

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Keeping track of symptoms and checking in with your provider can make it easier to fine-tune your plan

Metformin directly addresses insulin resistance, a core issue in PCOS that drives weight gain

[12] Poor sleep also tends to elevate ghrelin (the hunger hormone) whilst suppressing leptin (the satiety hormone), creating a hormonal environment that promotes overeating

Patient B: Jennifer, 43 Starting weight: 242 pounds Height: 57 Exercise approach: No resistance training, some walking, protein intake around 50-60g daily After 11 months: Weight: 168 pounds (74 pounds lost) Body fat: 34% (down from 43%) DEXA scan: 47 pounds fat lost, 27 pounds muscle lost Resting metabolic rate: Dropped 280 calories from baseline Clothing size: 22 to 12 Strength: Not assessed (no baseline) Jennifer looked deflated
