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In a randomized, placebo-controlled Phase 2a trial, PP405 met its primary safety endpoint and secondary pharmacokinetic endpoint, showed no systemic absorption, and was well tolerated across a diverse patient population

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We next investigated the metabolic changes undergoing tirzepatide and leptin coadministration

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The aim of this study is to evaluate the effectiveness of different treatments for GDM, such as metformin, insulin, or metformin in combination with insulin