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In Turners experience, living on these products is not fun

Nauck M, Frid A, Hermansen K, et al, for LEAD-2 Metformin Study Group

A likely mechanism behind this connection is the fact that GLP1 slows gut motility, which is a major cause of SIBO

It is important to note that there is no established direct causative mechanism linking GLP-1 receptor activation to increased gastric acid production or lower esophageal sphincter dysfunction

Consequently, effective management of patients with MASLD has become a critical clinical challenge

By activating GLP-1 receptors in the gut, these medications may help support the intestinal barrier function that is compromised in Hashimoto's patients