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All GLP-1 agonists labeled for weight reduction in cases of obesity or overweight plus one weight-related comorbidity must be combined with a reduced-calorie diet and increased physical activity

For some, appetite shifts may show up early, while for others, blood sugar or weight changes may take longer

Because of this, the drug is a good choice for people with diabetes and for anyone looking to lower their body weight

Remarkably there was a clear separation in what is called ACR50 in just the first 4 weeks of treatment in the patients taking tirzepatide plus Taltz together