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Semaglutide: review and place in therapy for adults with type 2 diabetes
Non-oral options like IUDs, implants, patches, vaginal rings, and injections bypass the digestive system entirely and are unaffected by GLP-1 medications

Early GLP-1 RAs (exenatide) [archived link] and exenatide ER [archived link]) were designed after a GLP-1 version found in Gila monster venom [archived link]

On October 1, the FDA approved Rhapsido (the first oral BTKi) for the treatment of chronic spontaneous urticaria, marking a new breakthrough in the field of immunology

In mice lacking SGLT1, peak glucose-triggered GLP-1 and GIP levels were impaired (Gorboulev et al., 2012), and L cells showed no calcium response to glucose intake (Parker et al., 2012a)

The gut microbiome also matters for metabolic health, especially for controlling abdominal fat that men tend to store more easily
