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Good hygiene and staying well-hydrated can reduce this risk

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As of 2025, retatrutide remains an investigational compound and has not received marketing authorisation from the Medicines and Healthcare products Regulatory Agency (MHRA) or the European Medicines Agency (EMA)

Patients who used semaglutide for 6+ months and made minimal lifestyle adjustments often experience stronger rebound than those who combined medication with behavioral changes

Data on study characteristics, patient demographics, and GLP-1 agonist use were collected

Linzess has been studied and approved for long-term use in managing chronic conditions like IBS-C and CIC