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Headaches are a recognized adverse effect of GLP-1 receptor agonist therapy, though they vary in frequency across different medications, doses, and patient populations

Diabetes - GLP-1 agonists should be primarily considered in patients with type 2 diabetes with suboptimal glycaemic control despite maximal tolerated dose of metformin (+/- other agents) especially where weight loss is desired and/or significant stroke risk is present

You will later learn how eating too fast and not properly chewing your food can lead to excessive swallowing of air (4, 19)

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however, it is important to note that these symptoms typically diminish with time and resolve on their own

Recent FDA guideline revisions now permit metformin use in mild-to-moderate CKD with appropriate eGFR-based dosing, expanding treatment options for millions of Americans with both conditions