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System One Reward Chemistry Hijacked is about how ultra-processed food substances flood the dopamine system, causing receptors to downregulate

The bigger and more efficient the engine, the more fuel it burns even when idling

It is well reviewed here (Smith et al, Nat Rev Nephrol 2019), and extremely reductively summarised as there being two major subgroups of C3G - dense deposit disease (DDD) and C3GN

Semaglutide also has benefits for cardiovascular and metabolic health, lowering cholesterol levels, blood pressure and risk of heart attack or stroke

Start with a low melatonin dose (0.51 mg) and use it only as needed during the first 24 weeks of semaglutide adjustment, when sleep changes are most common

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