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the strongest practical recommendation in 2026 is to combine that aerobic base with at least 23 dedicated resistance sessions per week

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FEBS Lett 1996

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Once cues hold high incentive salience, they become attractive, evoke intense craving, and trigger compulsive eating

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The resulting calcium influx and release lead to insulin granule exocytosis, which is supported by mitochondrial ATP synthesis

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Ghrelin Increases the Rewarding Value of High-Fat Diet in an Orexin-Dependent Manner

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This system becomes dysregulated in diabetes

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