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Nature 514:181186

The most common side effects are GI-related (nausea, diarrhea, constipation) and typically resolve by week 12

That's why it's sometimes called a triple-agonist or, more informally, "triple G"

In addition, binding studies suggested the presence of a large number of putative receptors for GLP-1 not only in the beta cells of the pancreatic islets but also in the brain (80)

Furthermore, in addition to incretin hormones, DPP-4 cleaves many other non-incretin peptides and regulates various biological processes

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