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Physical Activity: Regular physical activity is essential in managing body weight, blood pressure, and insulin sensitivity, which are crucial for people with type 2 diabetes and patients with obesity

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Methods Mice Wildtype C57BL/6JNarl male mice (6-8 weeks) were obtained from the National Laboratory Animal Center (NLAC), Taiwan

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All values were converted to concentration of cAMP using a cAMP standard curve performed in parallel, and data were subsequently normalized to the response of 100 nM forskolin