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In obese mice, Tirzepatide interventions have been shown to enhance -cell proliferation and function, reduce glucotoxicity, and extend life expectancy

Using both SGLT-2 and DPP-4 inhibitors as active comparators strengthened study validity, while register linkage minimized selection and recall bias by ensuring exposures were recorded independently of outcomes

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J Traditional Complement Med Luqman A, He M, Hassan A, Ullah M, Zhang L, Rashid Khan M, Din AU, Ullah K, Wang W, Wang G (2024) Mood and microbes: a comprehensive review of intestinal microbiotas impact on depression

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