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Previous serious hypersensitivity reactions, current pregnancy (especially for weight-loss indications), active pancreatitis and severe gastroparesis generally contraindicate use

In order to determine whether the genes found to be altered in the immortalized hypothalamic cell line were also expressed in the LH in vivo and altered by ingestion of fat, chow or sucrose, rats were exposed to respective diets for 1 h per day for 1 week on an every other day schedule

Without attorneys experienced in pharmaceutical causation issues and Daubert challenges, plaintiffs risk having their entire case dismissed before reaching settlement negotiations or trial

Given testing limitations, many practitioners recommend monitoring symptoms alongside or instead of laboratory testing

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further loss requires further intervention