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While Highsmith says the pill seems like a great option, she plans to stick with the weekly injectable for practical reasons

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It does not directly increase energy expenditure

Physical activity levels: Whilst exercise may feel challenging when fatigued, maintaining gentle activity can support energy regulation and metabolic adaptation

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Rusin D, Vahl Becirovic L, Lyszczarz G, Krueger M, Benmamar-Badel A, Vad Mathiesen C, Sigurardttir Schith E, Lykke Lambertsen K, Wlodarczyk A (2024) Microglia-derived insulin-like growth factor 1 is critical for neurodevelopment