first large study of glp-1 receptor agonists during pregnancy Glucagon-like peptide-1 receptor: mechanisms and advances in therapy Research shows GLP-1 receptor agonist
Description
Postprandial glucagon-like peptide-1 secretion is increased during the progression of glucose intolerance and obesity in high-fat/high-sucrose diet-fed rats

2020 Nov 5;80(3):485-500.e7

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Companies in this space include mitochondrial uncouplers with enhanced safety profiles (Rivus, Continuum), GDF15 targeting drugs (Novo, Lilly, Janssen), anti- activin II receptor mAb (Versanis), mir-22 inhibition (Resalis Tx) and gut-brain axis modulators (Kallyope)
A., Parkes, D

In these settings, GLP-1 therapies are often positioned as part of a broader service package that includes coaching, lifestyle guidance, and ongoing support
