glp-1 hairloss Hair loss has increasingly been reported among patients using and GIP agonists for weight loss. These include drugs like semaglutide, tirzepatide, liraglutide and others. Historically, this hair loss has been attributed GLP-1 therapies and hair loss:
Description
Heterotrimeric G protein activation by G-protein-coupled receptors

Meals shrink

These patients often experience multiple comorbidities, such as diabetes and cardiovascular disease, where GLP-1 therapies offer additional health benefits beyond weight loss
Many stimulants have potency at the rat TAAR1 in the micromolar range but tend to be about 5 to 10 times less potent at the human TAAR1, but bupropion was found to be inactive.87,88 "In Vitro Characterization of Psychoactive Substances at Rat, Mouse, and Human Trace Amine-Associated Receptor 1" (PDF)
Orforglipron doesn't match tirzepatide's 20% weight loss
[DOI] [PMC free article] [PubMed] [Google Scholar] 11.Rodriguez-Daza M.C., Pulido-Mateos E.C., Lupien-Meilleur J., Guyonnet D., Desjardins Y., Roy D