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Description
GLP-1RAs modulate immune cell signaling and regulate the nuclear factor-kappa B (NF-B) pathway, impacting inflammatory responses, cytokine production, and oxidative stress attenuation
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10.2337/dc14-2364 [DOI] [PubMed] [Google Scholar] 85.Goldenberg RM
Nieto L M et al
Trials investigating newer potential anti-obesity medications, including co-agonists and tri-agonists that target peptides such as GLP-1, glucose-dependent insulinotropic polypeptide (GIP), amylin, and glucagon are underway
Clinical trials lasting up to 52 weeks have shown a reduction in HbA1c levels of approximately 1% with DPP-4 inhibition (18)
