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A small bruise (dime-sized or smaller) after a thigh injection is normal and resolves within 3-7 days

Room temperature: If you didn't do so already, ensure your pen reaches room temperature before the injection, as this can minimize the stinging sensation

He has also served as Chief Medical Officer and Director of Hospital Medicine at New London HospitalDartmouth

Indeed, ectopic fat accumulation in the liver, together with hepatic inflammatory changes and insulin resistance, drives the progression from simple steatosis to non-alcoholic steatohepatitis (NASH) which can ultimately lead to liver cirrhosis, liver failure and hepatocellular carcinoma

This is one reason the stomach injection technique involves pinching a fold of skin, which ensures consistent subcutaneous delivery regardless of body fat percentage

During severe infections, it is often the immune systems response to LPS that becomes fatal