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The local increase in GIP stimulates vagal afferent transmission followed by activation of vagal efferents and enteric neurons that release acetylcholine and/or GRP to stimulate GLP-1 release from the distal gut

Manage stress: Stress can make heartburn symptoms worse

Patients on TRT or Hormone Optimization Programs Men on testosterone replacement therapy who carry significant excess body fat face a compound problem: elevated adipose tissue increases aromatase activity, converting more testosterone to estrogen, undermining the hormonal optimization they're investing in

Diabetes Care, 2020

It is critical that patients remember that these medications are not a magic bullet for weight loss and long-term weight management, notes Dr

doi: 10.2147/PTT.S485061
