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Davies M, Pieber TR, Hartoft-Nielsen ML, Hansen OKH, Jabbour S, Rosenstock J

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Helical peptides that are known to play key roles in maintaining metabolic homeostasis include, among others, glucagon (GCG) and glucagon-like peptide-1 (GLP-1), which signal and agonise the G-protein-coupled receptors (GPCR) GCGR and GLP-1R, respectively 1

36 Oral SNAC at 1 g/kg per day was also administered to pregnant Sprague-Dawley rats, resulting in a minor decrease in maternal body weights, prolonged gestation and an increase in stillbirths

doi: 10.1177/1479164111404257 97 Ben-ShlomoIYounisJS

There's a catch: researchers have found that oral semaglutide (Rybelsus) contains an absorption enhancer called salcaprozate sodium, which may enter milk and accumulate in infants