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PloS One (2011) 6(4):e19107

While laying on your left side, the esophagus is positioned above the stomach, which minimizes this effect

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Indeed, there is a growing body of evidence suggesting a significant beneficial class effect associated with SGLT2 inhibition, resulting in MACE, cardiovascular death and hospitalization for heart failure (HHF) reduction, despite some variabilities in the findings provided by individual CVOTs (40)

doi:10.1136/gutjnl-2014-308778 Wang Y, He J, Chen S, et al

Endocrinology (2016) 157:45619
