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Receptor binding and mechanism of action The main signaling mechanism of GLP-1 is the activation of adenylate cyclase via the Gs subunit, leading to increased production of cyclic AMP [6, 10]

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On top of this, there are hurdles that need to be overcome in terms of access and reimbursement of AOMs, and there are also strategic positioning considerations to facilitate a new drug becoming the first choice for patients and physicians

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In turn, this may change how effective the drug is in treating your condition

doi: 10.1016/j.vph.2017.10.002