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Mechanisms by which glucagon-like-Peptide-1 receptor agonists and sodium-glucose Cotransporter-2 inhibitors reduce Cardiovascular risk in adults with type 2 diabetes Mellitus
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In STEP 1, involving 1,961 participants, semaglutide resulted in a mean weight loss of 14.9% from baseline to week 68, compared to 2.4% with placebo, with 86.4% of semaglutide-treated participants achieving at least 5% weight reduction versus 31.5% on placebo
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