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We delineate how systemic metabolic dysfunction, often associated with obesity, synergizes with local inflammation to alter the balance between MMPs and their tissue inhibitors TIMPs, thus contributing to a perpetuating circle of inflammation and fibrosis

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Its frustrating to watch, given my field of study.

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Glucagonlike peptide 1 receptor agonists (GLP1RA) are commonly used as treatment for type 2 diabetes mellitus and obesity