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Your clinician can help decide if this class is a good fit for you based on your kidney function and overall risk profile

These regions are believed to be involved in many of the non-enzymatic functions of DPP-4, interacting with other proteins, such as adenosine deaminase, caveolin-1, streptokinase and plasminogen, and with components of the extracellular matrix (collagen, fibronectin), as well as functioning as binding sites for the chemokine CXCR4 receptor, the T-cell differentiation antigen, CD45, and the sodium-hydrogen exchanger-3, among others ( Table 1 The proline-specific peptidases

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These medicines, prescribed for type 2 diabetes and weight management, slow gastric emptying to regulate blood glucose and promote satiety

doi: 10.1038/s41591-024-03018-2

Sattar N, Lee MMY (2025) Estimating direct tissue effects versus weight loss effects of incretin-based drugs for obesity on various chronic conditions
