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Most of these medications can be continued on the day of surgery, with the critical exception of aspirin 81 mg, which should be stopped 7 days before surgery...

The hepatic TGF-/Smad signaling pathway was downregulated by SEMA treatment, while sirtuin 1 (SIRT1) content and phosphorylated AMP-activated protein kinase (p-AMPK) expression were upregulated

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