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Enteroendocrine L-cell derived peptide hormones, notably glucagon-like peptide-1 (GLP-1) and glucagon-like peptide-2 (GLP-2), have become important targets in the treatment of type 2 diabetes, obesity and intestinal diseases

Unlike the well-known roles of GLP-1 and #PYY, the role of INSL5 is poorly understood, but this new research suggests it promotes colonic motility and in fact may be behind the cases of severe diarrhea (bile acid malabsorption in #IBS)

Adults seeking improved digestive health and intestinal wellness

All of these unanswered questions only add to the urgency of determining who is most likely to benefit from GLP-1s. : Luliia Burmistrova / Getty

A Cox proportional hazard model was used to assess the cardiorenal protective effects between the GLP-1RA and DDP-4i groups