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From Semaglutide and Tirzepatide reduce alcohol consumption in individuals with obesity: In the remote study, we observe a significantly lower self-reported intake of alcohol, drinks per drinking episode, binge drinking odds, Alcohol Use Disorders Identification Test (AUDIT) scores, and stimulating, and sedative effects in the Semaglutide or Tirzepatide group when compared to prior to starting medication timepoint (within-subjects) and the control group (between-subjects)

doi: 10.1016/j.tem.2019.07.004 24 CarusoICignarelliANatalicchioAPerriniSLaviolaLGiorginoF

For diabetic retinopathy, the evidence was nuanced, indicating potential long-term neurovascular protection but also a risk of transient early worsening

CD11b serves as the alpha chain within the integrin CD11b/CD18 complex, which is found on the membranes of invading macrophages and neutrophils

Patients have even reported having to undergo gastric bypass as a result of severe medication-induced gastroparesis

3 Johns Hopkins Drug Discovery, Department of Neurology, Johns Hopkins School of Medicine, Baltimore, MD, 21205, USA Correspondence: Soo Kyung Bae, College of Pharmacy and Integrated Research Institute of Pharmaceutical Sciences, The Catholic University of Korea, Bucheon, 14662, Republic of Korea, Email [email protected] Abstract: Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are peptide-derived analogs that were initially investigated to treat type 2 diabetes