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Research shows both direct hormonal effects and indirect changes from rapid weight reduction can modify cycle regularity, flow, and timing

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The differential diagnosis includes pulmonary infections (Eisenmenger syndrome can cause decreased immune function), pulmonary vasoocclusive disease, aorto-pulmonary collaterals, as well as pulmonary artery in-situ thrombosis
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doi: 10.1159/000096742 69 SchmidtHSchwarzHP
