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If the enzymes increase or remain at the same level several days after introduction, the drug should be discontinued

FIGURE 3 Berberine increased the expression of PKA, PC1/3, PC2, and Pdx1 In the pancreas, we observed PC1/3 and PC2 under X400 microscope by immunohistochemical method (Figures 4A, B)

The evolution of obesity pharmacotherapy over the past decade follows a clear progression toward increasingly effective interventions

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